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Clopidogrel is a blood-thinning medicine. It prevents special cells in the blood -- the platelets -- from sticking to each other. This reduces the risk of harmful blood clots forming. Blood clots that form in a blood vessel inside the heart or brain can cause a heart attack or a stroke.

Clopidogrel is used to reduce the risk of heart attacks and strokes in people at high risk. This includes people who have had a heart attack or stroke before and are at risk of getting another one. It also includes people with blood circulation problems that may increase their chances of getting a heart attack or stroke.

Clopidogrel is also used together with aspirin to prevent blood clots in people who have had stents inserted into their heart arteries.

Clopidogrel may also be used to treat other conditions such as peripheral arterial disease (where there is some blockage or narrowing of arteries) or heart disease. How do I take this medicine? Take Clopidogrel exactly as directed by your doctor. Do not take more or less than instructed by your doctor.

Clopidogrel must be taken exactly as directed for it to work well. Continue taking Clopidogrel even when you feel better. Do not stop taking it unless instructed by your doctor.

You may take Clopidogrel with or without food. Try to take it at the same time each day. What should I do if I have forgotten to take this medicine? Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

Remember to take your medicine regularly. Clopidogrel must be taken exactly as directed for it to be effective. If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine? Alert your doctor immediately if you have a history of any of these conditions:

- bleeding disorders, for example, haemophilia
- stomach ulcers, especially if you have ever bled from a stomach ulcer
- low blood cell count (platelets, red or white blood cells)
- liver disease

Clopidogrel may increase the risk of abnormal bleeding. It is important to alert your doctor if you have any of these illnesses, as the risk of bleeding may be further increased.

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Visit your prescriber or health care professional for regular checks on your progress. Do not stop taking clopidogrel except on your prescriber's advice.

You may bleed more easily and it may take longer to stop bleeding when taking clopidogrel. Report any unusual bleeding to your prescriber.

Ask your prescriber or health care professional before you take non-prescription pain relievers. Do not take aspirin, aspirin-containing products, or antiinflammatory drugs such as ibuprofen (e.g, Motrin), ketoprofen, naproxen (e.g., Aleve) unless directed to do so by your prescriber or health care professional.

If you are going to have surgery or dental work, tell your prescriber or health care professional that you are taking clopidogrel.
What side effects may I notice from this medicine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

black, tarry stools
blood from vomiting
blood in urine or stools
nosebleed
red or purple spots on the skin
skin rash or itching
stomach pain
difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat fever
sudden weakness
swelling of your face, lips, tongue, hands, or feet
unusual bleeding or bruising, or pinpoint red spots on the skin
unusual rash, allergic reaction, or hives
unusually heavy menstrual bleeding

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

diarrhea
indigestion (heartburn)
mild stomach upset

This list may not describe all possible side effects. Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

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CLOPIDOGREL helps to prevent blood clots. It reduces the chance of having a heart attack or a stroke in people who have already had a heart attack or a stroke. Clopidogrel can also decrease the chance of a heart attack or stroke in certain groups of people at high risk for these events.
What should my health care professional know before I take this medicine?

They need to know if you have any of the following conditions:

bleeding disorder or hemophilia
liver disease
recent surgery or trauma
stomach or intestinal ulcers
an unusual or allergic reaction to clopidogrel, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

How should I take this medicine?

Take clopidogrel tablets by mouth. Swallow the tablets with a drink of water. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?

aspirin
blood thinners such as warfarin or enoxaparin
antiinflammatory drugs such as NSAIDs (e.g., ibuprofen)
cilostazol
dipyridamole
DHEA
ramelteon
tamoxifen
ticlopidine
tolbutamide
torsemide

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your physician or health care professional before stopping or starting any of your medicines.